Topiramate-induced nephrolithiasis
نویسندگان
چکیده
Nephrolithiasis is a less common side effect of the antiepileptic drug topiramate. We report the case of a 3-year-old boy who presented to the emergency department with abdominal pain; examinations revealed a large calcification in the left kidney. Regular ultrasound examinations are recommended in children using topiramate.
منابع مشابه
Topiramate-induced nephrolithiasis.
Topiramate is a recently developed antiepileptic medication that is becoming more widely prescribed because of its efficacy in treating refractory seizures. Urologists should be aware that this medication can cause metabolic acidosis in patients secondary to inhibition of carbonic anhydrase. In addition, a distal tubular acidification defect may result, thus impairing the normal compensatory dr...
متن کاملThe effects of topiramate on the acquisition and expression of morphine-induced place conditioning and behavioral sensitization in mice
Introduction: Topiramate is a newly anti-convulsant drug, which acts as NMDA glutamate receptor antagonist as well as the GABAB receptor agonist. It is used for physical dependence to opioids as well as cocaine, nicotine, alcohol and ecstasy dependence. In the present study attempts were made to further identification of the effects of topiramate on the acquisition and expression of morphine...
متن کاملTopiramate-induced Neuropathy Mimicking Carpal Tunnel Syndrome: A Case Report
Carpel tunnel syndrome (CTS) is a condition in which median nerve compression results in paresthesias and pain in thewrist and hand. We are going to report a rare case of topiramate-induced neuropathy which clinically resembles CTS.Discontinuation of topiramate resulted in spontaneous resolution of numbness, paresthesia and pain in a few days. Highclinical suspicion is advised in patients who a...
متن کاملTopiramate: a new antiepileptic drug for refractory epilepsy
Topiramate is a recently licensed and marketed antiepileptic drug in the UK for use as add-on therapy for refractory partial epilepsy. It has multiple modes of action involving voltage-dependent sodium channels, GABA receptors and glutamate receptors. Topiramate has very favourable pharmacokinetics as it is primarily excreted unchanged. Its metabolism is, however, increased by enzyme inducers, ...
متن کاملA Case Report of Topiramate-induced Acute Myopia
Acute myopia following use of some drugs is a relatively rare condition. Topiramate prescribed for seizure prophylaxis is one of these drugs. In this paper a case of acute transient myopia after taking topiramate is reported. The reported patient is a 28-year old woman who had no history of any eye disease. Following consumption of topiramate pill for one week, she had found blurred vision ...
متن کامل